Sandbox

• Description: general stress protein, survival of ethanol stress, SafA-dependent protein of the inner spore coat, spore cortex lytic protein
  
  

Gene name	yaaH
Synonyms	sleL
Essential	no
Product	N-acetylglucosaminidase
Function	survival of ethanol stress, protection of the spore
Gene expression levels in SubtiExpress: yaaH
MW, pI	48 kDa, 5.618
Gene length, protein length	1281 bp, 427 aa
Immediate neighbours	dgk, yaaI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

SigB regulon, SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: BSU00160

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • inner spore coat, localization depends on SafA PubMed

Database entries

• Structure:

• UniProt: P37531

• KEGG entry: [3]

• E.C. number:

Additional information

required for survival of ethanol stress PubMed

Expression and regulation

• Operon: yaaH PubMed

• Expression browser: yaaH PubMed

• Sigma factor: SigE PubMed, SigB PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • expressed during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: