CypC

• Description: long chain-fatty acid beta-hydroxylating cytochrome P450, H(2)O(2)-dependent, hydroxylates myristic acid to beta-hydroxymyristic acid, required for protection against paraquat stress
  
  

Gene name	cypC
Synonyms	ybdT
Essential	no
Product	fatty acid beta-hydroxylating cytochrome P450, protection against paraquat stress
Function	biosynthesis of beta-hydroxy fatty acid for lipopeptides
Gene expression levels in SubtiExpress: cypC
MW, pI	47 kDa, 6.468
Gene length, protein length	1251 bp, 417 aa
Immediate neighbours	ybxI, ybyB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress, electron transport/ other, lipid metabolism/ other

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU02100

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • hydroxylation of a long-chain fatty acid (e.g. myristic acid) at the alpha- and beta-positions using hydrogen peroxide as an oxidant PubMed

• Protein family: cytochrome P450 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2ZQJ 1IZOPubMed

• UniProt: O31440

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cypC (according to DBTBS)

• Expression browser: cypC PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: