SpoVK

• Description: required for spore maturation
  
  

Gene name	spoVK
Synonyms	spoVJ
Essential	no
Product	unknown
Function	spore maturation
Gene expression levels in SubtiExpress: spoVK
MW, pI	36 kDa, 8.825
Gene length, protein length	966 bp, 322 aa
Immediate neighbours	cwlC, ynbA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU17420

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: cbxX/cfxQ family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P27643

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVK PubMed

• Expression browser: spoVK PubMed

• Sigma factor: SigE PubMed, SigK PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE, SigK) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S99 ( spoVK::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

N Fan, S Cutting, R Losick
Characterization of the Bacillus subtilis sporulation gene spoVK.
J Bacteriol: 1992, 174(3);1053-4
[PubMed:1732196] [WorldCat.org] [DOI] (P p)

D Foulger, J Errington
Sequential activation of dual promoters by different sigma factors maintains spoVJ expression during successive developmental stages of Bacillus subtilis.
Mol Microbiol: 1991, 5(6);1363-73
[PubMed:1787791] [WorldCat.org] [DOI] (P p)

J Errington, L Wootten, J C Dunkerley, D Foulger
Differential gene expression during sporulation in Bacillus subtilis: regulation of the spoVJ gene.
Mol Microbiol: 1989, 3(8);1053-60
[PubMed:2514336] [WorldCat.org] [DOI] (P p)