MenA

• Description: probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
  
  

Gene name	menA
Synonyms	ywaB, ipa-6d
Essential	yes PubMed
Product	probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
Function	biosynthesis of menaquinone
Gene expression levels in SubtiExpress: menA
Metabolic function and regulation of this protein in SubtiPathways: Menaquinone
MW, pI	33 kDa, 9.32
Gene length, protein length	933 bp, 311 aa
Immediate neighbours	ywaC, ywzH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU38490

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: menA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39582

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: menA PubMed

• Expression browser: menA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933] [WorldCat.org] [DOI] (P p)