SpoIIID

• Description: transcriptional regulator (repressor or activator) of a subset of sigma-E-dependent genes
  
  

Gene name	spoIIID
Synonyms
Essential	no
Product	transcriptional regulator
Function	regulation of mother cell gene expression
Gene expression levels in SubtiExpress: spoIIID
Metabolic function and regulation of this protein in SubtiPathways: Asp, Asn, Cell wall
MW, pI	10 kDa, 9.496
Gene length, protein length	279 bp, 93 aa
Immediate neighbours	mbl, usd
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU36420

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: binds its DNA targets as a monomeric protein (possible due to the two DNA-binding motifs) PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: two DNA-binding regions: HTH at the N-terminus and a basic region near the C-terminus PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2L0K (complex with DNA)

• UniProt: P15281

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: usd-spoIIID-mbl-flhO-flhP PubMed

• Expression browser: spoIIID PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed
• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed