GlcK

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  • Description: glucose kinase (D-glucose:ATP)

Gene name glcK
Synonyms yqgR
Essential no
Product glucose kinase (D-glucose:ATP)
Function phosphorylation of the free glucose moiety
resulting from cleavage of di-and oligosaccharides
Gene expression levels in SubtiExpress: glcK
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism, Sugar catabolism
MW, pI 33 kDa, 5.988
Gene length, protein length 963 bp, 321 aa
Immediate neighbours yqgS, yqgQ
Sequences Protein DNA DNA_with_flanks
Genetic context
GlcK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GlcK expression.png




























Categories containing this gene/protein

utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU24850

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + D-glucose = ADP + D-glucose 6-phosphate (according to Swiss-Prot)
  • Protein family: ROK (nagC/xylR) family (according to Swiss-Prot)
  • Paralogous protein(s): XylR

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2QM1 (from Enterococcus faecalis, 38% identity, 52% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP2 (spc), available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References