SsuD

• Description: aliphatic sulfonate monooxygenase
  
  

Gene name	ssuD
Synonyms	ygcA, yzeC
Essential	no
Product	aliphatic sulfonate monooxygenase
Function	sulfonate reduction
Gene expression levels in SubtiExpress: ssuD
Metabolic function and regulation of this protein in SubtiPathways: Cys, Met & Sulfate assimilation
MW, pI	41 kDa, 5.369
Gene length, protein length	1128 bp, 376 aa
Immediate neighbours	ssuC, ygaN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sulfur metabolism

This gene is a member of the following regulons

CymR regulon

The gene

Basic information

• Locus tag: BSU08860

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: An alkanesufonate (R-CH(2)-SO₃H) + FMNH₂ + O₂ = an aldehyde (R-CHO) + FMN + sulfite + H₂O (according to Swiss-Prot)

• Protein family: ssuD family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1NQK (from Escherichia coli, 64% identity, 76% similarity)

• UniProt: P40402

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ssuB-ssuA-ssuC-ssuD-ygaN PubMed

• Expression browser: ssuD PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed in the presence of cysteine (CymR) PubMed

• Regulatory mechanism:
  • CymR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:
  • 1A951 ( ssuD::cat), PubMed, available at BGSC
  • 1A8083 ( ssuD::kan), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: