PhrK

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Gene name phrK
Synonyms
Essential no
Product phosphatase (RapK) regulator
Function control of ComA activity
Gene expression levels in SubtiExpress: phrK
Interactions involving this protein in SubtInteract: PhrK
MW, pI 3 kDa, 8.158
Gene length, protein length 120 bp, 40 aa
Immediate neighbours rapK, yobH
Sequences Protein DNA Advanced_DNA
Genetic context
PhrK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhrK expression.png
























Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing, short peptides

This gene is a member of the following regulons

AbrB regulon, SigH regulon

The gene

Basic information

  • Locus tag: BSU18920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: inhibits RapK activity PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)