CotC

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  • Description: spore coat protein (outer)

Gene name cotC
Synonyms
Essential no
Product spore coat protein (outer)
Function resistance of the spore
Gene expression levels in SubtiExpress: cotC
Interactions involving this protein in SubtInteract: CotC
MW, pI 14 kDa, 9.558
Gene length, protein length 354 bp, 118 aa
Immediate neighbours ynzK, tatAC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CotC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotC expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon, SpoIIID regulon

The gene

Basic information

  • Locus tag: BSU17700

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • outer spore coat, more abundant at the mother cell-distal pole of the forespore PubMed
    • the CotC-CotU complex assembles around the forming spore PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: cotC (according to DBTBS)
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Application of CotZ for protein surface display

Setareh Tavassoli, Krzysztof Hinc, Adam Iwanicki, Michal Obuchowski, Gholamreza Ahmadian
Investigation of spore coat display of Bacillus subtilis β-galactosidase for developing of whole cell biocatalyst.
Arch Microbiol: 2013, 195(3);197-202
[PubMed:23334774] [WorldCat.org] [DOI] (I p)