YloI

• Description: Coenzyme A biosynthesis bifunctional protein CoaBC; putative phosphopantothenoylcysteine synthetase/decarboxylase
  
  

Gene name	yloI
Synonyms	coaBC
Essential	no
Product	putative phosphopantothenoylcysteine synthetase/decarboxylase
Function	biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: yloI
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	43 kDa, 6.013
Gene length, protein length	1218 bp, 406 aa
Immediate neighbours	yloH, priA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU15700

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O35033

• KEGG entry: [2]

• E.C. number: 4.1.1.36

Expression and regulation

• Operon:

• Expression browser: yloI PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Germán Plata, Tobias Fuhrer, Tzu-Lin Hsiao, Uwe Sauer, Dennis Vitkup
Global probabilistic annotation of metabolic networks enables enzyme discovery.
Nat Chem Biol: 2012, 8(10);848-54
[PubMed:22960854] [WorldCat.org] [DOI] (I p)