SigG
- Description: RNA polymerase sporulation forespore-specific (late) sigma factor SigG
Gene name | sigG |
Synonyms | spoIIIG |
Essential | no |
Product | RNA polymerase sporulation forespore-specific (late) sigma factor SigG |
Function | transcription of sporulation genes (late forespore) |
Gene expression levels in SubtiExpress: sigG | |
Interactions involving this protein in SubtInteract: SigG | |
MW, pI | 29 kDa, 5.496 |
Gene length, protein length | 780 bp, 260 aa |
Immediate neighbours | sigE, ylmA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context ![]() This image was kindly provided by SubtiList
| |
Expression at a glance PubMed![]() |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, sporulation proteins
This gene is a member of the following regulons
AbrB regulon, SigF regulon, SigG regulon, SinR regulon, Spo0A regulon
The SigG regulon
The gene
Basic information
- Locus tag: BSU15330
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s): SigF
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
Database entries
- Structure:
- UniProt: P19940
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Reviews
Michiel J L de Hoon, Patrick Eichenberger, Dennis Vitkup
Hierarchical evolution of the bacterial sporulation network.
Curr Biol: 2010, 20(17);R735-45
[PubMed:20833318]
[WorldCat.org]
[DOI]
(I p)
The SigG regulon
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Original Publications
Additional publications: PubMed
Lamya Rhayat, Sandra Duperrier, Rut Carballido-López, Olivier Pellegrini, Patrick Stragier
Genetic dissection of an inhibitor of the sporulation sigma factor sigma(G).
J Mol Biol: 2009, 390(5);835-44
[PubMed:19497328]
[WorldCat.org]
[DOI]
(I p)
Amy H Camp, Richard Losick
A feeding tube model for activation of a cell-specific transcription factor during sporulation in Bacillus subtilis.
Genes Dev: 2009, 23(8);1014-24
[PubMed:19390092]
[WorldCat.org]
[DOI]
(I p)
Mónica Serrano, Filipe Vieira, Charles P Moran, Adriano O Henriques
Processing of a membrane protein required for cell-to-cell signaling during endospore formation in Bacillus subtilis.
J Bacteriol: 2008, 190(23);7786-96
[PubMed:18820020]
[WorldCat.org]
[DOI]
(I p)
Amy H Camp, Richard Losick
A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels.
Mol Microbiol: 2008, 69(2);402-17
[PubMed:18485064]
[WorldCat.org]
[DOI]
(I p)
Takao Igarashi, Peter Setlow
Transcription of the Bacillus subtilis gerK operon, which encodes a spore germinant receptor, and comparison with that of operons encoding other germinant receptors.
J Bacteriol: 2006, 188(11);4131-6
[PubMed:16707705]
[WorldCat.org]
[DOI]
(P p)
Louise Evans, Andrea Feucht, Jeff Errington
Genetic analysis of the Bacillus subtilis sigG promoter, which controls the sporulation-specific transcription factor sigma G.
Microbiology (Reading): 2004, 150(Pt 7);2277-2287
[PubMed:15256570]
[WorldCat.org]
[DOI]
(P p)
Mónica Serrano, Alexandre Neves, Cláudio M Soares, Charles P Moran, Adriano O Henriques
Role of the anti-sigma factor SpoIIAB in regulation of sigmaG during Bacillus subtilis sporulation.
J Bacteriol: 2004, 186(12);4000-13
[PubMed:15175314]
[WorldCat.org]
[DOI]
(P p)
Louise Evans, Joanna Clarkson, Michael D Yudkin, Jeff Errington, Andrea Feucht
Analysis of the interaction between the transcription factor sigmaG and the anti-sigma factor SpoIIAB of Bacillus subtilis.
J Bacteriol: 2003, 185(15);4615-9
[PubMed:12867473]
[WorldCat.org]
[DOI]
(P p)
Mónica Serrano, Luísa Côrte, Jason Opdyke, Charles P Moran, Adriano O Henriques
Expression of spoIIIJ in the prespore is sufficient for activation of sigma G and for sporulation in Bacillus subtilis.
J Bacteriol: 2003, 185(13);3905-17
[PubMed:12813085]
[WorldCat.org]
[DOI]
(P p)
A Cabrera-Hernandez, P Setlow
Analysis of the regulation and function of five genes encoding small, acid-soluble spore proteins of Bacillus subtilis.
Gene: 2000, 248(1-2);169-81
[PubMed:10806362]
[WorldCat.org]
[DOI]
(P p)
I Bagyan, B Setlow, P Setlow
New small, acid-soluble proteins unique to spores of Bacillus subtilis: identification of the coding genes and regulation and function of two of these genes.
J Bacteriol: 1998, 180(24);6704-12
[PubMed:9852018]
[WorldCat.org]
[DOI]
(P p)
C Fabret, J A Hoch
A two-component signal transduction system essential for growth of Bacillus subtilis: implications for anti-infective therapy.
J Bacteriol: 1998, 180(23);6375-83
[PubMed:9829949]
[WorldCat.org]
[DOI]
(P p)
M Gomez, S M Cutting
Expression of the Bacillus subtilis spoIVB gene is under dual sigma F/sigma G control.
Microbiology (Reading): 1996, 142 ( Pt 12);3453-7
[PubMed:9004507]
[WorldCat.org]
[DOI]
(P p)
E M Kellner, A Decatur, C P Moran
Two-stage regulation of an anti-sigma factor determines developmental fate during bacterial endospore formation.
Mol Microbiol: 1996, 21(5);913-24
[PubMed:8885263]
[WorldCat.org]
[DOI]
(P p)
R Schmidt, A L Decatur, P N Rather, C P Moran, R Losick
Bacillus subtilis lon protease prevents inappropriate transcription of genes under the control of the sporulation transcription factor sigma G.
J Bacteriol: 1994, 176(21);6528-37
[PubMed:7961403]
[WorldCat.org]
[DOI]
(P p)
D Foulger, J Errington
Effects of new mutations in the spoIIAB gene of Bacillus subtilis on the regulation of sigma F and sigma G activities.
J Gen Microbiol: 1993, 139(12);3197-203
[PubMed:8126438]
[WorldCat.org]
[DOI]
(P p)
S R Partridge, J Errington
The importance of morphological events and intercellular interactions in the regulation of prespore-specific gene expression during sporulation in Bacillus subtilis.
Mol Microbiol: 1993, 8(5);945-55
[PubMed:8355618]
[WorldCat.org]
[DOI]
(P p)
J Errington, L Appleby, R A Daniel, H Goodfellow, S R Partridge, M D Yudkin
Structure and function of the spoIIIJ gene of Bacillus subtilis: a vegetatively expressed gene that is essential for sigma G activity at an intermediate stage of sporulation.
J Gen Microbiol: 1992, 138(12);2609-18
[PubMed:1487728]
[WorldCat.org]
[DOI]
(P p)
N Illing, J Errington
Genetic regulation of morphogenesis in Bacillus subtilis: roles of sigma E and sigma F in prespore engulfment.
J Bacteriol: 1991, 173(10);3159-69
[PubMed:1902463]
[WorldCat.org]
[DOI]
(P p)
D X Sun, R M Cabrera-Martinez, P Setlow
Control of transcription of the Bacillus subtilis spoIIIG gene, which codes for the forespore-specific transcription factor sigma G.
J Bacteriol: 1991, 173(9);2977-84
[PubMed:1902213]
[WorldCat.org]
[DOI]
(P p)
P Fajardo-Cavazos, F Tovar-Rojo, P Setlow
Effect of promoter mutations and upstream deletions on the expression of genes coding for small, acid-soluble spore proteins of Bacillus subtilis.
J Bacteriol: 1991, 173(6);2011-6
[PubMed:1900507]
[WorldCat.org]
[DOI]
(P p)
Y Nakatani, W L Nicholson, K D Neitzke, P Setlow, E Freese
Sigma-G RNA polymerase controls forespore-specific expression of the glucose dehydrogenase operon in Bacillus subtilis.
Nucleic Acids Res: 1989, 17(3);999-1017
[PubMed:2493633]
[WorldCat.org]
[DOI]
(P p)
D X Sun, P Stragier, P Setlow
Identification of a new sigma-factor involved in compartmentalized gene expression during sporulation of Bacillus subtilis.
Genes Dev: 1989, 3(2);141-9
[PubMed:2497051]
[WorldCat.org]
[DOI]
(P p)
R M Jonas, E A Weaver, T J Kenney, C P Moran, W G Haldenwang
The Bacillus subtilis spoIIG operon encodes both sigma E and a gene necessary for sigma E activation.
J Bacteriol: 1988, 170(2);507-11
[PubMed:2448286]
[WorldCat.org]
[DOI]
(P p)