MoaD

• Description: molybdopterin synthase (small subunit)
  
  

Gene name	moaD
Synonyms
Essential	no
Product	molybdopterin synthase (small subunit)
Function	nitrate respiration
Gene expression levels in SubtiExpress: moaD
Interactions involving this protein in SubtInteract: MoaD
MW, pI	7 kDa, 3.829
Gene length, protein length	231 bp, 77 aa
Immediate neighbours	moaE, yknU
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU14310

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • MoaD-MoaE (as deduced from E. coli, PubMed)

• Localization:

Database entries

• Structure:
  • 1NVI (the MoaD-MoaE complex from E. coli) PubMed

• UniProt: O31706

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: mobA-moeB-moeA-mobB-moaE-moaD PubMed

• Expression browser: moaD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866] [WorldCat.org] [DOI] (I p)