PanC

From SubtiWiki
Revision as of 08:50, 16 April 2012 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: pantothenate synthase

Gene name panC
Synonyms
Essential no
Product pantothenate synthase
Function biosynthesis of coenzyme A
Metabolic function and regulation of this protein in SubtiPathways:
Coenzyme A
MW, pI 31 kDa, 4.626
Gene length, protein length 858 bp, 286 aa
Immediate neighbours panD, panB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PanC context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22420

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate (according to Swiss-Prot)
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2EJC (from Thermotoga maritima, 50% identity, 66% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References