SpoVM

• Description: required for normal spore cortex and coat synthesis, inhibits the proteolytic activity of FtsH (adaptor protein)
  
  

Gene name	spoVM
Synonyms
Essential	no
Product	spore coat morphogenetic protein
Function	spore cortex and coat synthesis
Interactions involving this protein in SubtInteract: SpoVM
MW, pI	2 kDa, 11.026
Gene length, protein length	78 bp, 26 aa
Immediate neighbours	yloS, rpmB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU15810

Phenotypes of a mutant

• reduction of sporulation efficiency due to defects in spore coat and cortex assembly PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • anchors the basement layer of the spore coat to the surface of the developing spore PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SpoIVA-SpoVM-SpoVID PubMed

• Localization:
  • around the surface of the developing forespore PubMed
  • spore membrane, recognizes membrane curvature PubMed

Database entries

• Structure:

• UniProt: P37817

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVM PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed in mother cell during sporulation (SigE, SpoIIID) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: