DeoR

• Description: transcriptional repressor of the dra-nupC-pdp operon
  
  

Gene name	deoR
Synonyms	yxxC
Essential	no
Product	transcriptional repressor
Function	regulation of deoxyribonucleotide utilization
Metabolic function and regulation of this protein in SubtiPathways: Nucleoside catabolism, Nucleotides (regulation)
MW, pI	35 kDa, 6
Gene length, protein length	939 bp, 313 aa
Immediate neighbours	dra, yxxB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of nucleotides, transcription factors and their control

The DeoR regulon:

• dra-nupC-pdp

The gene

Basic information

• Locus tag: BSU39430

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription repression of the dra-nupC-pdp operon

• Protein family: sorC transcriptional regulatory family (according to Swiss-Prot) DeoR family of transcription repressors

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39140

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: deoR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

X Zeng, H H Saxild, R L Switzer
Purification and characterization of the DeoR repressor of Bacillus subtilis.
J Bacteriol: 2000, 182(7);1916-22
[PubMed:10714997] [WorldCat.org] [DOI] (P p)

X Zeng, H H Saxild
Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis.
J Bacteriol: 1999, 181(6);1719-27
[PubMed:10074062] [WorldCat.org] [DOI] (P p)

H H Saxild, L N Andersen, K Hammer
Dra-nupC-pdp operon of Bacillus subtilis: nucleotide sequence, induction by deoxyribonucleosides, and transcriptional regulation by the deoR-encoded DeoR repressor protein.
J Bacteriol: 1996, 178(2);424-34
[PubMed:8550462] [WorldCat.org] [DOI] (P p)