LytC
- Description: N-acetylmuramoyl-L-alanine amidase, required for flagellar function PubMed
| Gene name | lytC |
| Synonyms | cwlB |
| Essential | no |
| Product | N-acetylmuramoyl-L-alanine amidase
(EC 3.5.1.28) |
| Function | major autolysin, cell separation, wall turnover
lysis, motility and general cell lysis induced by sodium azide |
| MW, pI | 52 kDa, 10.108 |
| Gene length, protein length | 1488 bp, 496 aa |
| Immediate neighbours | tuaA, lytB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
cell wall degradation/ turnover, motility and chemotaxis
This gene is a member of the following regulons
LytR regulon, SigD regulon, SlrR regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU35620
Phenotypes of a mutant
impaired in motility, the phenotype is suppressed by mutations in lonA or smiA PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)
- Protein family: N-acetylmuramoyl-L-alanine amidase 3 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: secreted (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q02114
- KEGG entry: [3]
- E.C. number: 3.5.1.28
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
