GerE

• Description: transcriptional regulator required for the expression of SigK-dependent late spore coat genes
  
  

Gene name	gerE
Synonyms
Essential	no
Product	transcriptional regulator (LuxR-FixJ family)
Function	regulation of SigK-dependent gene expression
Function and regulation of this protein in SubtiPathways: Phosphorelay, Protein secretion
MW, pI	8 kDa, 9.635
Gene length, protein length	222 bp, 74 aa
Immediate neighbours	ysmB, ysmA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transcription factors and their control, germination

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

• Locus tag: BSU28410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LuxR-FixJ family of transcription regulators

• Paralogous protein(s):

Genes controlled by GerE

lipC, surC

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1FSE

• UniProt: P11470

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: gerE PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Arthur Aronson, Purdue University, West Lafayette, USA homepage
• Charles Moran, Emory University, NC, USA homepage