SpeE

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  • Description: spermidine synthase

Gene name speE
Synonyms ywhF
Essential no
Product spermidine synthase
Function spermidine, polyamine biosynthesis
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 31 kDa, 5.068
Gene length, protein length 828 bp, 276 aa
Immediate neighbours speB, pbpG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpeE context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

miscellaneous metabolic pathways

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU37500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine (according to Swiss-Prot)
  • Protein family: spermidine/spermine synthase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

A Sekowska, P Bertin, A Danchin
Characterization of polyamine synthesis pathway in Bacillus subtilis 168.
Mol Microbiol: 1998, 29(3);851-8
[PubMed:9723923] [WorldCat.org] [DOI] (P p)