PksS

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  • Description: cytochrome P450, hydroxylase of the polyketide bacillaene produced by the pks cluster

Gene name pksS
Synonyms
Essential no
Product hydroxylase of the polyketide produced by the pks cluster
Function polyketide synthesis
MW, pI 43 kDa, 6.121
Gene length, protein length 1128 bp, 376 aa
Immediate neighbours pksR, ymzB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PksS context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU17230

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hydroxylation of dihydrobacillaene PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jason J Reddick, Stephanie A Antolak, Gregory M Raner
PksS from Bacillus subtilis is a cytochrome P450 involved in bacillaene metabolism.
Biochem Biophys Res Commun: 2007, 358(1);363-7
[PubMed:17482575] [WorldCat.org] [DOI] (P p)