ArfM

• Description: regulation of anaerobic genes
  
  

Gene name	arfM
Synonyms	ywiD
Essential	no
Product	unknown
Function	regulation of anaerobic genes
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism, Stress
MW, pI	17 kDa, 5.842
Gene length, protein length	474 bp, 158 aa
Immediate neighbours	narG, ywiC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU37290

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

regulators of electron transport, transcription factors and their control

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P46910

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: arfM PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • expressed under anaerobic conditions (Fnr) PubMed

• Regulatory mechanism:
  • Fnr: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Heike Reents, Richard Münch, Thorben Dammeyer, Dieter Jahn, Elisabeth Härtig
The Fnr regulon of Bacillus subtilis.
J Bacteriol: 2006, 188(3);1103-12
[PubMed:16428414] [WorldCat.org] [DOI] (P p)

M Marino, H C Ramos, T Hoffmann, P Glaser, D Jahn
Modulation of anaerobic energy metabolism of Bacillus subtilis by arfM (ywiD).
J Bacteriol: 2001, 183(23);6815-21
[PubMed:11698370] [WorldCat.org] [DOI] (P p)

H Cruz Ramos, L Boursier, I Moszer, F Kunst, A Danchin, P Glaser
Anaerobic transcription activation in Bacillus subtilis: identification of distinct FNR-dependent and -independent regulatory mechanisms.
EMBO J: 1995, 14(23);5984-94
[PubMed:8846791] [WorldCat.org] [DOI] (P p)