VmlR

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  • Description: ABC transporter (ATP-binding protein), efflux of antibiotics (virginiamycin M, lincomycin)

Gene name vmlR
Synonyms expZ
Essential no
Product antibiotic efflux ABC transporter (ATP-binding protein)
Function efflux of antibiotics (virginiamycin M, lincomycin)
MW, pI 62 kDa, 6.727
Gene length, protein length 1641 bp, 547 aa
Immediate neighbours ydgE, ydgF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ExpZ context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU05610

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: has both a membrane-spanning and an ATP-binding domain PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by virginiamycin M or lincomycin PubMed
  • Regulatory mechanism: transcriptional antitermination, details are unknown PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References