CotD

• Description: spore coat protein (inner)
  
  

Gene name	cotD
Synonyms
Essential	no
Product	spore coat protein (inner)
Function	resistance of the spore
MW, pI	8 kDa, 7.373
Gene length, protein length	225 bp, 75 aa
Immediate neighbours	ypsA, yprB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU22200

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: inner spore coat PubMed

Database entries

• Structure:

• UniProt: P07791

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotD (according to DBTBS)

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: