AraP

• Description: L-arabinose transport (integral membrane protein)
  
  

Gene name	araP
Synonyms	yseD
Essential	no
Product	L-arabinose transport (integral membrane protein))
Function	uptake of arabinose
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	34 kDa, 9.69
Gene length, protein length	939 bp, 313 aa
Immediate neighbours	araQ, araN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU28740

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: MalFG subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P94529

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: araA-araB-araD-araL-araM-araN-araP-araQ-abfA

• Sigma factor: SigA

• Regulation: repressed by glucose (CcpA)
  • repressed in the absence of arabinose (AraR) PubMed

• Regulatory mechanism: CcpA: transcription repression
  • AraR: transcription repression PubMed

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Inácio JM, Costa C, de Sá-Nogueira I. (2003) Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis. Microbiology. Sep;149(Pt 9): 2345-55. PubMed
2. Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. (1997) The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology. Mar;143(Pt 3): 957-69. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed