RocD
- Description: ornithine transaminase
| Gene name | rocD |
| Synonyms | |
| Essential | no |
| Product | ornithine transaminase |
| Function | arginine, ornithine and citrulline utilization |
| MW, pI | 43 kDa, 4.894 |
| Gene length, protein length | 1203 bp, 401 aa |
| Immediate neighbours | rocE, rocR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU40340
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid (according to Swiss-Prot)
- Protein family: OAT subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P38021
- KEGG entry: [3]
- E.C. number: 2.6.1.13
Additional information
Expression and regulation
- Regulatory mechanism: RocR, AhrC: transcription activation PubMed, CodY: transcription repression PubMed
- Additional information:
Biological materials
- Mutant: GP656, aphA3, available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
R Gardan, G Rapoport, M Débarbouillé
Expression of the rocDEF operon involved in arginine catabolism in Bacillus subtilis.
J Mol Biol: 1995, 249(5);843-56
[PubMed:7540694]
[WorldCat.org]
[DOI]
(P p)
