LysM domain

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LysM domains have affinity for N-acetylglucosamine polymers (GlcNac) in the lower μM range. A single LysM domain is able to bind carbohydrate ligands and LysM domains act additively to increase the binding-affinity.

B. subtilis proteins containing a LysM domain

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Important reviews

Important original publications

Jaslyn E M M Wong, Husam M A B Alsarraf, Jørn Døvling Kaspersen, Jan Skov Pedersen, Jens Stougaard, Søren Thirup, Mickaël Blaise
Cooperative binding of LysM domains determines the carbohydrate affinity of a bacterial endopeptidase protein.
FEBS J: 2014, 281(4);1196-208
[PubMed:24355088] [WorldCat.org] [DOI] (I p)


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