FadM

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  • Description: fatty acid degradation, similar to proline dehydrogenase

Gene name fadM
Synonyms yusM
Essential no
Product unknown
Function fatty acid degradation
Gene expression levels in SubtiExpress: fadM
Metabolic function and regulation of this protein in SubtiPathways:
Fatty acid degradation
MW, pI 34 kDa, 9.377
Gene length, protein length 906 bp, 302 aa
Immediate neighbours yuzL, yuzM
Sequences Protein DNA DNA_with_flanks
Genetic context
YusM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FadM expression.png




























Categories containing this gene/protein

utilization of lipids

This gene is a member of the following regulons

FadR regulon, SdpR regulon

The gene

Basic information

  • Locus tag: BSU32850

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor (according to Swiss-Prot)
  • Protein family: proline dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s): PutB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086] [WorldCat.org] [DOI] (I p)