RbsA

• Description: ribose ABC transporter (ATP-binding protein)
  
  

Gene name	rbsA
Synonyms
Essential	no
Product	ribose ABC transporter (ATP-binding protein)
Function	ribose uptake
Gene expression levels in SubtiExpress: rbsA
Interactions involving this protein in SubtInteract: RbsA
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	54 kDa, 6.179
Gene length, protein length	1479 bp, 493 aa
Immediate neighbours	rbsD, rbsC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon

The gene

Basic information

• Locus tag: BSU35940

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + H₂O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In) (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RbsA(2)-(RbsC-RbsD)-RbsB PubMed

• Localization: attached to the cell membrane (via RbsC-RbsD) PubMed

Database entries

• Structure:

• UniProt: P36947

• KEGG entry: [3]

• E.C. number: 3.6.3.17

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Expression browser: rbsA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: