PanC

• Description: pantothenate synthase
  
  

Gene name	panC
Synonyms
Essential	no
Product	pantothenate synthase
Function	biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: panC
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	31 kDa, 4.626
Gene length, protein length	858 bp, 286 aa
Immediate neighbours	panD, panB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU22420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate (according to Swiss-Prot)

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2EJC (from Thermotoga maritima, 50% identity, 66% similarity)

• UniProt: P52998

• KEGG entry: [2]

• E.C. number: 6.3.2.1

Expression and regulation

• Operon:

• Expression browser: panC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: