PenP

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  • Description: beta-lactamase

Gene name penP
Synonyms
Essential no
Product beta-lactamase
Function resistance to beta-lactam antibiotics
Gene expression levels in SubtiExpress: penP
MW, pI 33 kDa, 9.208
Gene length, protein length 918 bp, 306 aa
Immediate neighbours yoaZ, yobA
Sequences Protein DNA Advanced_DNA
Genetic context
PenP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PenP expression.png
























Categories containing this gene/protein

resistance against toxins/ antibiotics

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU18800

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: A beta-lactam + H2O = a substituted beta-amino acid (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3KGM (from B. licheniformis, 58% identity, 79% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References