TatAY

• Description: component of the TatAY-TatCY twin-arginine translocase
  
  

Gene name	tatAY
Synonyms	ydiI
Essential	no
Product	component of the twin-arginine translocation pathway
Function	TAT protein secretion
Gene expression levels in SubtiExpress: tatAY
Interactions involving this protein in SubtInteract: TatAY
Metabolic function and regulation of this protein in SubtiPathways: Protein secretion
MW, pI	5 kDa, 6.558
Gene length, protein length	171 bp, 57 aa
Immediate neighbours	rex, tatCY
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein secretion, membrane proteins

The gene

Basic information

• Locus tag: BSU05980

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: secretion of YwbN and of YkuE

• Protein family: tatA/E family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • TatAY-TatCY PubMed
  • WprA-TatAY PubMed
  • TatAY-TatAD PubMed
  • TatAC-TatAY PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O05522

• KEGG entry: [2]

• E.C. number:

Additional information

• TatAY-TatCY-dependent export of YkuE and YwbN requires a functional WprA PubMed

Expression and regulation

• Operon:
  • ydiG-rex-tatAY-tatCY PubMed
  • tatAY-tatCY PubMed

• Expression browser: tatAY PubMed

• Sigma factor:

• Regulation: constitutitvely expressed PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878] [WorldCat.org] [DOI] (I e)