NtdR

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Gene name ntdR
Synonyms yhjM
Essential no
Product transcriptional regulator (LacI family)
Function regulation of the ntdA-ntdB-ntdC-glcP operon
Gene expression levels in SubtiExpress: ntdR
MW, pI 37 kDa, 6.645
Gene length, protein length 987 bp, 329 aa
Immediate neighbours ntdA, yhjN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhjM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NtdR expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, transcription factors and their control, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon

The NtdR regulon:

The gene

Basic information

  • Locus tag: BSU10560

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed

Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753] [WorldCat.org] [DOI] (P p)

Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444] [WorldCat.org] [DOI] (P p)