RbsA

• Description: ribose ABC transporter (ATP-binding protein)
  
  

Gene name	rbsA
Synonyms
Essential	no
Product	ribose ABC transporter (ATP-binding protein)
Function	ribose uptake
Interactions involving this protein in SubtInteract: RbsA
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	54 kDa, 6.179
Gene length, protein length	1479 bp, 493 aa
Immediate neighbours	rbsD, rbsC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon

The gene

Basic information

• Locus tag: BSU35940

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + H₂O + monosaccharide(Out) = ADP + phosphate + monosaccharide(In) (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RbsA(2)-(RbsC-RbsD)-RbsB PubMed

• Localization: attached to the cell membrane (via RbsC-RbsD) PubMed

Database entries

• Structure:

• UniProt: P36947

• KEGG entry: [3]

• E.C. number: 3.6.3.17

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Expression browser: rbsA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: