SpoIIE
- Description: protein serine phosphatase, septum-associated PP2C, dephosphorylation of SpoIIAA
| Gene name | spoIIE |
| Synonyms | spoIIH, spoIIK |
| Essential | no |
| Product | protein serine phosphatase, septum-associated PP2C |
| Function | control of SigF activity required for normal formation of the asymmetric septum |
| Interactions involving this protein in SubtInteract: SpoIIE | |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 91 kDa, 6.137 |
| Gene length, protein length | 2481 bp, 827 aa |
| Immediate neighbours | trnSL-Glu1, yabS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
protein modification, sigma factors and their control, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
- Protein family: PP2C phosphatase
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
- localizes to the polar cell division sites where it causes FtsZ to relocate from mid-cell to form polar Z-rings
Database entries
- KEGG entry: [3]
- E.C. number: 3.1.3.16
Additional information
Expression and regulation
- Operon: spoIIE (DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
Your additional remarks
References
Additional publications: PubMed
