YhfU

• Description: high capacity biotin transporter
  
  

Gene name	yhfU
Synonyms	bioY
Essential	no
Product	high capacity biotin transporter
Function	uptake of biotin
MW, pI	19 kDa, 10.681
Gene length, protein length	558 bp, 186 aa
Immediate neighbours	yhfT, hemAT
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, biosynthesis of cofactors, membrane proteins

The gene

Basic information

• Locus tag: BSU10370

Expression

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: uptake of biotin PubMed

• Protein family: bioY family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

• Structure:

• UniProt: O07620

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Peter Hebbeln, Dmitry A Rodionov, Anja Alfandega, Thomas Eitinger
Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module.
Proc Natl Acad Sci U S A: 2007, 104(8);2909-14
[PubMed:17301237] [WorldCat.org] [DOI] (P p)