MenA

• Description: probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
  
  

Gene name	menA
Synonyms	ywaB, ipa-6d
Essential	yes PubMed
Product	probable 1,4-dihydroxy-2-naphthoate octaprenyltransferase
Function	biosynthesis of menaquinone
Metabolic function and regulation of this protein in SubtiPathways: Menaquinone
MW, pI	33 kDa, 9.32
Gene length, protein length	933 bp, 311 aa
Immediate neighbours	ywaC, dltA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU38490

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: menA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P39582

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: menA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

E Presecan, I Moszer, L Boursier, H Cruz Ramos, V de la Fuente, M-F Hullo, C Lelong, S Schleich, A Sekowska, B H Song, G Villani, F Kunst, A Danchin, P Glaser
The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).
Microbiology (Reading): 1997, 143 ( Pt 10);3313-3328
[PubMed:9353933] [WorldCat.org] [DOI] (P p)