SpoVE

• Description: required for spore cortex peptidoglycan synthesis
  
  

Gene name	spoVE
Synonyms
Essential	no
Product	unknown
Function	spore cortex peptidoglycan synthesis
Metabolic function and regulation of this protein in SubtiPathways: Cell wall
MW, pI	39 kDa, 9.853
Gene length, protein length	1098 bp, 366 aa
Immediate neighbours	murD, murG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU15210

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, sporulation proteins, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)

• Paralogous protein(s): FtsW, RodA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • SpoVD-SpoVE PubMed, this protects SpoVE from proteolytic degradation PubMed

• Localization: integral membrane protein, forespore PubMed

Database entries

• Structure:

• UniProt: P07373

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • murE-mraY-murD-spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • spoVE-murG-murB-divIB-ylxW-ylxX-sbp PubMed
  • spoVE PubMed

• Sigma factor:
  • spoVE: SigE PubMed

• Regulation:
  • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: