PepT

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  • Description: peptidase T (tripeptidase), zinc-dependent

Gene name pepT
Synonyms
Essential no
Product peptidase T (tripeptidase)
Function peptide degradation
MW, pI 45 kDa, 4.538
Gene length, protein length 1230 bp, 410 aa
Immediate neighbours yxjL, yxjJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PepT context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38920

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of the N-terminal residue from a tripeptide (according to Swiss-Prot)
  • Protein family: peptidase M20B family (according to Swiss-Prot)
  • Paralogous protein(s): YqjE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

M H Cha, W M Yong, S M Lee, Y S Lee, I Y Chung
The biochemical and molecular characterization of recombinant Bacillus subtilis tripeptidase (PepT) as a zinc-dependent metalloenzyme.
Mol Cells: 2000, 10(4);423-31
[PubMed:10987140] [WorldCat.org] (P p)

O Schrögel, O Krispin, R Allmansberger
Expression of a pepT homologue from Bacillus subtilis.
FEMS Microbiol Lett: 1996, 145(3);341-8
[PubMed:8978088] [WorldCat.org] [DOI] (P p)