yxjL

168

two-component response regulator

Locus: BSU_38910

Molecular weight: 24.10 kDa

Isoelectric point: 5.36

Protein length: 218 aa

Gene length: 657 bp

Function: unknown

Product: two-component response regulator

Essential: no

Synonyms: yxjL

Genomic Context

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List of homologs in different organisms, belongs to COG2197 (Galperin et al., 2021)

Gene

Coordinates: 3,994,369  3,995,025

The protein

Domains

• Response regulatory domain (aa 7-123) (according to UniProt)
• HTH luxR-type domain (aa 150-215) (according to UniProt)

Structure

• 5HEV (PDB) (LiaR from Enterococcus faecium, 41% identity) PubMed
• P55184 (AlphaFold)

Modification

• phosphorylation by YxjM

Paralogous protein(s)

• LnrK, LiaR, YhcZ, YdfI

Biological materials

Mutant

• MGNA-B805 (yxjL::erm), available at the NBRP B. subtilis, Japan
• BKE38910 (yxjL::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCATCGGCAAGCGCTACGC,  downstream forward: _UP4_TAGAAATCTCTCATCCCGCC
• BKK38910 (yxjL::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ATCATCGGCAAGCGCTACGC,  downstream forward: _UP4_TAGAAATCTCTCATCCCGCC

References

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