MmgA

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  • Description: degradative acetoacetyl-CoA thiolase

Gene name mmgA
Synonyms yqiL
Essential no
Product degradative acetoacetyl-CoA thiolase
Function mother cell metabolism
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 41 kDa, 5.904
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours mmgB, yqiK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MmgA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 2 acetyl-CoA = CoA + acetoacetyl-CoA (according to Swiss-Prot)
  • Protein family: thiolase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References


  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed