KdgA

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  • Description: 2-dehydro-3-deoxy-phosphogluconate aldolase

Gene name kdgA
Synonyms
Essential no
Product 2-dehydro-3-deoxy-phosphogluconate aldolase
Function utilization of galacturonic acid
MW, pI 20 kDa, 5.273
Gene length, protein length 588 bp, 196 aa
Immediate neighbours kdgT, kdgK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
KdgA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU22100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate (according to Swiss-Prot)
  • Protein family: anti-sigma-factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Petar Pujic, Rozenn Dervyn, Alexei Sorokin, S Dusko Ehrlich
The kdgRKAT operon of Bacillus subtilis: detection of the transcript and regulation by the kdgR and ccpA genes.
Microbiology (Reading): 1998, 144 ( Pt 11);3111-3118
[PubMed:9846747] [WorldCat.org] [DOI] (P p)


  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed