kdgT

168

2-keto-3-deoxygluconate permease

Locus: BSU_22090

Molecular weight: 34.16 kDa

Isoelectric point: 8.94

Protein length: 330 aa

Gene length: 993 bp

Function: utilization of galacturonic acid

Product: 2-keto-3-deoxygluconate permease

Essential: no

Synonyms: kdgT

Genomic Context

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List of homologs in different organisms

Gene

Coordinates: 2,321,972 → 2,322,964

The protein

Protein family

• KdgT transporter family (single member, according to UniProt)

Structure

• P50847 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: kdgR-kdgK-kdgA-kdgT

  Description: PubMed

  Regulation

  • induced by galacturonate (KdgR) PubMed

  Regulatory mechanism

  • KdgR: repression, PubMed, in kdgR regulon
  • CcpA: repression, PubMed, in ccpA regulon

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Additional information

• translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

Mutant

• BKE22090 (ΔkdgT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGTGGATTCTCCCAT,  downstream forward: _UP4_TGAATAAAAAGGCTGCCACA
• BKK22090 (ΔkdgT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGTGGATTCTCCCAT,  downstream forward: _UP4_TGAATAAAAAGGCTGCCACA

References

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