Sandbox

• Description: inhibitor of pro-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-SigK processing

Caution: The sequence for this gene in SubtiList contains errors
Gene name	bofA
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Synonyms
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Essential	no
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Product
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Function	inhibition of the pro-	Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
Caution: The sequence for this gene in SubtiList contains errors
MW, pI	8 kDa, 9.32
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Gene length, protein length	261 bp, 87 aa
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Immediate neighbours	yaaL, [[rrnA-	Caution: The sequence for this gene in SubtiList contains errors
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[http://subtiwiki.uni-	Caution: The sequence for this gene in SubtiList contains errors
[http://subtiwiki.uni-	Caution: The sequence for this gene in SubtiList contains errors
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Genetic context
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The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: BofA-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-SpoIVB PubMed

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon: bofA PubMed

• Sigma factor: SigE PubMed

• Regulation: expressed during sporulation PubMed

• Regulatory mechanism: repressed by SpoIIID PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-hybrid system:

• Antibody:

Labs working on this gene/protein

Simon Cutting, London, UK homepage

References

1. Dong & Cutting (2004) The PDZ domain of the SpoIVB transmembrane signaling protein enables cis-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-trans interactions involving multiple partners leading to the activation of the pro- |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-sigmaK processing complex in Bacillus subtilis.J. Biol. Chem. 279: 43468- |colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-43478. PubMed

1. Ireton & Grossman (1992 ) Interactions among mutations that cause altered timing of gene expression during sporulation in Bacillus subtilis. J. Bacteriol. 174: 3185-

|colspan="2" style="background:#FAF8CC;color:#FF0000" align="center" | Caution: The sequence for this gene in SubtiList contains errors |-3195. PubMed