GsaB

• Description: glutamate-1-semialdehyde aminotransferase
  
  

Gene name	gsaB
Synonyms
Essential	no
Product	glutamate-1-semialdehyde aminotransferase
Function	biosynthesis of heme
Gene expression levels in SubtiExpress: gsaB
Metabolic function and regulation of this protein in SubtiPathways: GsaB
MW, pI	46 kDa, 5.644
Gene length, protein length	1287 bp, 429 aa
Immediate neighbours	ygaE, ygaF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU08710

Database entries

• BsubCyc: BSU08710

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate (according to Swiss-Prot)

• Protein family: HemL subfamily (according to Swiss-Prot)

• Paralogous protein(s): HemL

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU08710

• Structure: 3BS8 (HemL) PubMed

• UniProt: P71084

• KEGG entry: [2]

• E.C. number: 5.4.3.8

Expression and regulation

• Operon:

• Expression browser: gsaB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 531 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1080 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: