PepT

• Description: peptidase T (tripeptidase), zinc-dependent
  
  

Gene name	pepT
Synonyms
Essential	no
Product	peptidase T (tripeptidase)
Function	peptide degradation
Gene expression levels in SubtiExpress: pepT
Metabolic function and regulation of this protein in SubtiPathways: pepT
MW, pI	45 kDa, 4.538
Gene length, protein length	1230 bp, 410 aa
Immediate neighbours	yxjL, yxjJ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

The gene

Basic information

• Locus tag: BSU38920

Database entries

• BsubCyc: BSU38920

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Release of the N-terminal residue from a tripeptide (according to Swiss-Prot)

• Protein family: peptidase M20B family (according to Swiss-Prot)

• Paralogous protein(s): YqjE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU38920

• Structure: 3GBO (from Bacillus cereus (71% identity), to be published)

• UniProt: P55179

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pepT PubMed

• Expression browser: pepT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

M H Cha, W M Yong, S M Lee, Y S Lee, I Y Chung
The biochemical and molecular characterization of recombinant Bacillus subtilis tripeptidase (PepT) as a zinc-dependent metalloenzyme.
Mol Cells: 2000, 10(4);423-31
[PubMed:10987140] [WorldCat.org] (P p)

O Schrögel, O Krispin, R Allmansberger
Expression of a pepT homologue from Bacillus subtilis.
FEMS Microbiol Lett: 1996, 145(3);341-8
[PubMed:8978088] [WorldCat.org] [DOI] (P p)