GltP

• Description: similar to H+/glutamate symporter
  
  

Gene name	gltP
Synonyms
Essential	no
Product	similar to H+/glutamate symporter
Function	unknown
Gene expression levels in SubtiExpress: gltP
Metabolic function and regulation of this protein in SubtiPathways: gltP
MW, pI	44 kDa, 8.651
Gene length, protein length	1242 bp, 414 aa
Immediate neighbours	ybfQ, gamP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, membrane proteins

The gene

Basic information

• Locus tag: BSU02340

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Additional information

• A mutation was found in this gene after evolution under relaxed selection for sporulation PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: View classification (according to Swiss-Prot)

• Paralogous protein(s): GltT, DctP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 4KY0 (the glutamate transporter of Thermococcus kodakarensis, 33% identity, 68% similarity) PubMed

• UniProt: P39817

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: gltP PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Sonja Jensen, Albert Guskov, Stephan Rempel, Inga Hänelt, Dirk Jan Slotboom
Crystal structure of a substrate-free aspartate transporter.
Nat Struct Mol Biol: 2013, 20(10);1224-6
[PubMed:24013209] [WorldCat.org] [DOI] (I p)

Christopher T Brown, Laura K Fishwick, Binna M Chokshi, Marissa A Cuff, Jay M Jackson, Travis Oglesby, Alison T Rioux, Enrique Rodriguez, Gregory S Stupp, Austin H Trupp, James S Woollcombe-Clarke, Tracy N Wright, William J Zaragoza, Jennifer C Drew, Eric W Triplett, Wayne L Nicholson
Whole-genome sequencing and phenotypic analysis of Bacillus subtilis mutants following evolution under conditions of relaxed selection for sporulation.
Appl Environ Microbiol: 2011, 77(19);6867-77
[PubMed:21821766] [WorldCat.org] [DOI] (I p)

B Tolner, T Ubbink-Kok, B Poolman, W N Konings
Characterization of the proton/glutamate symport protein of Bacillus subtilis and its functional expression in Escherichia coli.
J Bacteriol: 1995, 177(10);2863-9
[PubMed:7751298] [WorldCat.org] [DOI] (P p)