YukD

• Description: Ubiquitin-like protein, part of the type VII protein secretion system YukD-YukC-YukB-YueB-YueC, putative bacteriocin
  
  

Gene name	yukD
Synonyms
Essential	no
Product	ubiquitin-like protein, part of the type VII protein secretion system, putative bacteriocin
Function	export of YukE
Gene expression levels in SubtiExpress: yukD
MW, pI	8 kDa, 6.311
Gene length, protein length	237 bp, 79 aa
Immediate neighbours	yukC, yukE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of antibacterial compounds, protein secretion

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

• Locus tag: BSU31900

Database entries

• BsubCyc: BSU31900

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU31900

• Structure: 2BPS

• UniProt: P71071

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yukE-yukD-yukC-yukB-yueB-yueC PubMed

• Expression browser: yukD PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • not expressed in the lab strain 168, due to lack of DegU-P PubMed
  • expressed in the stationary phase PubMed

• Regulatory mechanism:
  • DegU-P: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Roxane Simeone, Daria Bottai, Roland Brosch
ESX/type VII secretion systems and their role in host-pathogen interaction.
Curr Opin Microbiol: 2009, 12(1);4-10
[PubMed:19155186] [WorldCat.org] [DOI] (I p)

Mark J Pallen
The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system?
Trends Microbiol: 2002, 10(5);209-12
[PubMed:11973144] [WorldCat.org] [DOI] (P p)