HemA

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  • Description: glutamyl-tRNA reductase

Gene name hemA
Synonyms
Essential no
Product glutamyl-tRNA reductase
Function porphyrin biosynthesis
Gene expression levels in SubtiExpress: hemA
MW, pI 50 kDa, 5.313
Gene length, protein length 1365 bp, 455 aa
Immediate neighbours hemX, ysxD
Sequences Protein DNA DNA_with_flanks
Genetic context
HemA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HemA expression.png
























Categories containing this gene/protein

biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU28170

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-glutamate 1-semialdehyde + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + NADPH (according to Swiss-Prot)
  • Protein family: glutamyl-tRNA reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References