HemL

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  • Description: glutamate-1-semialdehyde aminotransferase

Gene name hemL
Synonyms hemK
Essential no
Product glutamate-1-semialdehyde aminotransferase
Function heme biosynthesis
Gene expression levels in SubtiExpress: hemL
MW, pI 46 kDa, 5.055
Gene length, protein length 1290 bp, 430 aa
Immediate neighbours spoVID, hemB
Sequences Protein DNA DNA_with_flanks
Genetic context
HemL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HemL expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU28120

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate (according to Swiss-Prot)
  • Protein family: HemL subfamily (according to Swiss-Prot)
  • Paralogous protein(s): GsaB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References