SpoVE

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  • Description: required for spore cortex peptidoglycan synthesis

Gene name spoVE
Synonyms
Essential no
Product unknown
Function spore cortex peptidoglycan synthesis
Gene expression levels in SubtiExpress: spoVE
Interactions involving this protein in SubtInteract: SpoVE
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 39 kDa, 9.853
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours murD, murG
Sequences Protein DNA DNA_with_flanks
Genetic context
SpoVE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoVE expression.png




























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

  • Locus tag: BSU15210

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed during vegatative growth, then switched off, and again expressed during sporulation in the mother cell (SigE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Allison Fay, Pablo Meyer, Jonathan Dworkin
Interactions between late-acting proteins required for peptidoglycan synthesis during sporulation.
J Mol Biol: 2010, 399(4);547-61
[PubMed:20417640] [WorldCat.org] [DOI] (I p)

Gonçalo Real, Allison Fay, Avigdor Eldar, Sérgio M Pinto, Adriano O Henriques, Jonathan Dworkin
Determinants for the subcellular localization and function of a nonessential SEDS protein.
J Bacteriol: 2008, 190(1);363-76
[PubMed:17981970] [WorldCat.org] [DOI] (I p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

G Theeragool, A Miyao, K Yamada, T Sato, Y Kobayashi
In vivo expression of the Bacillus subtilis spoVE gene.
J Bacteriol: 1993, 175(13);4071-80
[PubMed:8320223] [WorldCat.org] [DOI] (P p)

A O Henriques, H de Lencastre, P J Piggot
A Bacillus subtilis morphogene cluster that includes spoVE is homologous to the mra region of Escherichia coli.
Biochimie: 1992, 74(7-8);735-48
[PubMed:1391053] [WorldCat.org] [DOI] (P p)