YloI

• Description: Coenzyme A biosynthesis bifunctional protein CoaBC; putative phosphopantothenoylcysteine synthetase/decarboxylase
  
  

Gene name	yloI
Synonyms	coaBC
Essential	no
Product	putative phosphopantothenoylcysteine synthetase/decarboxylase
Function	biosynthesis of coenzyme A
Gene expression levels in SubtiExpress: yloI
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	43 kDa, 6.013
Gene length, protein length	1218 bp, 406 aa
Immediate neighbours	yloH, priA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU15700

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O35033

• KEGG entry: [2]

• E.C. number: 4.1.1.36

Expression and regulation

• Operon:

• Expression browser: yloI PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Germán Plata, Tobias Fuhrer, Tzu-Lin Hsiao, Uwe Sauer, Dennis Vitkup
Global probabilistic annotation of metabolic networks enables enzyme discovery.
Nat Chem Biol: 2012, 8(10);848-54
[PubMed:22960854] [WorldCat.org] [DOI] (I p)